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May 11 at 5:45 comment added LazyReader The point is, that computing models have allowed chemists to produce a yield simuluation of how it will interact before manufacturing resources are dedicated to it's production.
May 10 at 22:17 comment added uhoh @TylerSterling " I want to ask what major breakthroughs have been made in theoretical and computational chemistry in the last 30 years." I think this fit nicely within the scope of that sentence, the way it is written in the question.
May 10 at 16:47 comment added Tyler Sterling I like this answer and +1'd it, but the OP specifically asked about methods development (i.e. theoretical methods) and this answer only mentions advances in computing resources.
May 10 at 2:24 history answered LazyReader CC BY-SA 4.0