I have performed an ABF simulation to investigate the binding of a small molecule with a 2D surface using NAMD. The initial simulation was for a scan window of 3 to 15 angstroms of z-projected distance between the small molecule and the 2D surface. However, upon analyzing the data, I observed that the sampling between the region 7-15 angstrom were significantly lower when compared to the 3-7 angstrom region. Thus, I performed an another ABF run between 7 and 15 angstroms. Is there a way I can combine these two data to generate the full 3-15 scan range?



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