I have two main modeling research lines: one related to structural biology (including rational drug design, de novo design, polymorphism, etc.) and the other one related to condensed matter (nanostructures, crystals, etc.).
Any time I submit a manuscript in the biological area, either the editors or the reviewers ask for experimental validation, even when we use very well established simulation tools to make the predictions (here we work only with small molecules and proteins, not with living organism simulations). On the other hand, when submitting a manuscript in the condensed matter area, we never received that complaint.
What are some of the theoretical results in matter modeling that correctly predict experimental results and can be the cause for the confidence and reliability of the predictions made?