I was performing MD simulation for protein-ligand complex
following [GROMACS tutorial][1].

I compared the  energy of two ligands (S1 and S2) to a protein,
using GROMACS **LJ-SR** (Lennard-Jones Short Range) and **Coul-SR** (Coulombic Short Range) option.

Below is the plot.

[![enter image description here][2]][2]


As you can see the LJ-SR is complete opposite of Coul-SR.
Are they expected to be the opposite?
Which is more appropriate choice to represent real binding energy?


  [1]: http://www.mdtutorials.com/gmx/complex/09_analysis.html
  [2]: https://i.sstatic.net/fTY3N.png